Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Woischnik, M.; Bauer, A.; Aboutaam, R.; Pamir, A.; Stanzel, F.; de Blic, J.; Griese, M.
    Cathepsin H and napsin A are active in the alveoli and increased in alveolar proteinosis (2008), Eur. Respir. J., 31, 1197-1204.
    View publication on PubMed

Application

EC Number Application Comment Organism
3.4.23.B1 medicine studies on differentiation of primary from secondary effects in the pathogenesis of juvenile and adult forms of Pulmonary alveolar proteinosis Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.22.16 cystatin C physiological inhibitor of cathepsin H Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.22.16 Homo sapiens P09668
-
-
3.4.23.B1 Homo sapiens O96009
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.22.16 alveolus
-
 Homo sapiens
-
3.4.22.16 bronchoalveolar lavage fluid
-
 Homo sapiens
-
3.4.22.16 lung
-
 Homo sapiens
-
3.4.23.B1 bronchoalveolar system bronchoalveolar lavage fluid (BALF), expression in Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.23.B1 additional information
-
 amounts and activities of napsin A studied by immunoblotting and specific substrate cleavage, general defect in napsin A expression or activity not observed as cause for abnormal surfactant accumulation in juvenile pulmonary alveolar proteinosis Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.23.B1 additional information napsin A expression analyzed in juvenile and adult forms of Pulmonary alveolar proteinosis (PALP) Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.23.B1 napsin A
-
 Homo sapiens